Nutritional aspects in dermatology

Abstract

The literature review was developed based on the analysis of contemporary specialized scientific information, published between 2018 and 2023, using databases such as PubMed, NCBI, Z-library, Medscape, and Mendeley, applying the following keywords: „diseases”, „skin”, „foods”, „role”, „mechanism”, „nutrients”, „relationship”, and „diet”, which were combined in various ways. Numerous studies have demonstrated a positive association between poor nutrition and the aggravation of skin diseases by maintaining systemic and local inflammation in dermatological lesions via IL-6 and TNF-α. In conditions of chronic inflammatory stress, the herpes virus is activated, leading to recurrent skin lesions. Increased production of TNF-α promotes the expansion of T-helper 17 (Th17) cells, leading to elevated IL-17A levels, which play a key role in the pathogenesis of psoriasis. Excessive consumption of 07cereals and soy milk, which are rich in phytates and organic phosphates, can compromise enterocyte integrity, contributing to the development of inflammatory bowel disease. This, in turn, may lead to significant losses of essential minerals (Zn and Fe), which can contribute to the development of angular cheilitis and enteropathic acrodermatitis, as well as deficiencies in vitamins A, B, C, and niacin, which can lead to conditions such as pellagra and scurvy. Furthermore, deficiencies in other essential nutrients can negativele impact skin integrity. The link between nutrition and skin health is undeniable. A well-balanced, nutrient-dense diet provides the building blocks needed for skin structure, function, and resilience. Thus, by adopting healthy eating habits, individuals can proactively contribute to the health and appearance of their skin.