Generalized candidemia in a patient post COVID- 19 - the differential diagnosis

Authors

  • Rodica Bugai Nicolae Testemițanu State University of Medicine and Pharmacy
  • Veronica Cazacu "Saint Archangel Michael" Municipal Clinical Hospital
  • Ion Garstea "Saint Archangel Michael" Municipal Clinical Hospital
  • Svetlana Postoronca "Saint Archangel Michael" Municipal Clinical Hospital
  • Loretta Esanu "Saint Archangel Michael" Municipal Clinical Hospital
  • Maria Feghiu Nicolae Testemițanu State University of Medicine and Pharmacy
  • Ghenadie Bezu Nicolae Testemițanu State University of Medicine and Pharmacy https://orcid.org/0000-0002-8453-651X
  • Svetlana Chislaru "Saint Archangel Michael" Municipal Clinical Hospital

Keywords:

COVID-19, candidemia

Abstract

The clinical case of a 74-year-old patient with severe pancytopenia, which appeared after infection with SARS-CoV2, was described. The given case is of interest due to the difficulty of establishing the diagnosis and the severity of the evolution of the disease. Pancytopenia appeared during the course of suffering from COVID-19 and progressed in the post-COVID-19 period during about 3 months, with the worsening of the patient’s general condition, the development of generalized candidemia, and death, despite the treatment administered. The difficulty of establishing the diagnosis in the post-COVID19 period is of interest. Candidiasis, an opportunistic fungal infection, has become more prevalent as the world continues to battle COVID-19. It is crucial to understand the pathogenesis and mechanism of virulence to shed light on disease progression, especially in co-infections. The different factors that predispose patients with COVID-19 to candidiasis, their interactions, and individual effects must be well understood to prevent the development of opportunistic co-infections that drastically decrease patients’ chances of survival.

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Published

2026-04-26

How to Cite

[1]
Bugai, R. et al. 2026. Generalized candidemia in a patient post COVID- 19 - the differential diagnosis. Public Health Economy and Management in Medicine. 2(93) (Apr. 2026), 156–161.

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