Some considerations of clinical aspects and treatment in digestive non-Hodgkin's lymphomas
DOI:
https://doi.org/10.52556/2587-3873.2023.4(97).18Keywords:
Non-Hodgkin lymphoma, gastrointestinal tract, treatment, surgery, chemotherapy, radiotherapyAbstract
The gastrointestinal tract is the most common primary location for extranodal non-Hodgkin lymphomas (NHL), and due to nonspecific symptoms, diagnosis may be delayed. Combined or complex treatment allows good tumor control. The purpose of the paper was to evaluate the clinical and treatment aspects of digestive NHL for the optimization of therapeutic tactics. Material and methods. The clinical and treatment aspects of 55 patients diagnosed with digestive NHL were studied. Results. It was determined that digestive NHLs developed more frequently in patients aged 51-60 years (34,5%). Gastric localization was found most frequently (76.4%). Although damage to the esophagus is exceptionally rare, a case was encountered during this period. According to the degree of spread of the tumor process, most patients were diagnosed in stage IV (61.8%), demonstrating a late addressability and an unfavorable prognosis in the future. The treatment carried out was more often constituted by chemotherapy, followed by the association of surgical treatment. Radiotherapy has been used to enhance the effect, with good tumor control, or palliatively. Conclusions. The combined and complex treatment can significantly increase the effectiveness of the treatment and decrease the frequency of relapses, which can improve the survival rate.
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