Medicamentele cu efect hipoglicemiant secundar
DOI:
https://doi.org/10.52556/2587-3873.2024.5(102).15Cuvinte cheie:
hipoglicemie medicamentoasă, interacţiunimedicamentoase, beta-blocante, fluorochinoloneRezumat
A fost studiată problema hipoglicemiei induse de medicamentele non-diabetice, care este tot mai des raportată. Efectul secundar hipoglicemic al medicamentelor este explicat prin diferite mecanisme și se manifestă individual în funcție de vârstă, gen, comorbidități. Un rol aparte revine administrării asociate a medicamentelor și interacțiunii dintre ele. Au fost selectate și analizate datele din literatura de specialitate (rapoarte de caz și baze de date medicale), cu scopul de a identifica medicamentele cu potențial hipoglicemiant, mecanismele de acțiune, factorii de risc asociați, inclusiv strategiile de prevenire și gestionare a hipoglicemiei induse medicamentos. Studiul raportează o varietate de medicamente non-antidiabetice, a căror administrare este asociată cu riscul dezvoltării hipoglicemiei, inclusiv beta-blocantele, fluorochinolonele, inhibitorii enzimei de conversie (IEC) ş.a. Au fost detalizate mecanismele prin care acestea pot afecta nivelurile de glucoză, importanţa monitorizării atente a pacienţilor, precum şi ajustării tratamentului. Hipoglicemia indusă de medicamente reprezintă o problemă clinică semnificativă, care necesită o abordare multidisciplinară în vederea prevenirii și gestionării acesteia. Educația pacientului și o comunicare eficientă între medic și pacient sunt esențiale pentru minimizarea riscurilor și îmbunătățirea siguranței tratamentului.
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