Antibiotic-associated diarrhea: risk factors, clinical forms and treatment
DOI:
https://doi.org/10.52556/2587-3873.2025.2(104).19Keywords:
antibiotic-associated diarrhea, risk factors, intestinalmicroflora, Clostridioides difficile, treatment, antibioticstewardshipAbstract
This literature review examines existing data on antibioticassociated diarrhea (AAD), focusing on the identification of risk factors, characterization of clinical forms, and evaluation of the efficacy of various therapeutic regimens. A systematic search of major reference databases revealed a substantial body of studies highlighting the role of antibiotic administration, the impact of intestinal microflora imbalance, and the importance of implementing antibiotic stewardship programs. Key findings include variations in AAD incidence according to the type of antibiotics used and patient predisposition based on demographic factors and comorbidities. The results indicate the need to develop an integrated diagnostic and treatment algorithm to optimize clinical interventions and reduce associated costs.
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