Hipogonadismul bărbatului în vârstă. Repere de diagnostic și tratament

Ion Dumbraveanu; Iurii Arian; Victoria Ghenciu; Mariana Creciun; Emil Ceban

doi:10.52556/2587-3873.2024.5(102).21

Hipogonadismul bărbatului în vârstă. Repere de diagnostic și tratament

Autori

Ion Dumbraveanu Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0000-0003-1114-2189
Iurii Arian Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0000-0003-1436-5230
Victoria Ghenciu Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0009-0000-5001-5137
Mariana Creciun Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0000-0002-4771-5703
Emil Ceban Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0000-0002-1583-2884

DOI:

https://doi.org/10.52556/2587-3873.2024.5(102).21

Cuvinte cheie:

hipogonadism asociat vârstei, hipogonadismcu debut tardiv, hipogonadism funcțional, terapie desubstituție hormonală

Rezumat

Hipogonadismul masculin asociat vârstei este cea mai controversată formă de hipogonadism și o problemă neelucidată. Prevalența sa nu este cunoscută, cifrele estimative arătând că cel puțin 1 din 5 bărbați după vârsta de 40 ani și circa 80% din cei cu comorbidități pot avea hipogonadism. Hipogonadismul cu debut tardiv al bărbatului nu are criterii definite ale vârstei și poate include în mecanismele sale declanșatoare și evolutive elemente de hipogonadism primar, datorat funcției testiculare insuficiente, și hipogonadism secundar. La elaborarea acestui articol au fost consultate review-urile a 40 de studii analitice și ghiduri internaționale ale Academiei Europene de Andrologie și ale Societăților de Endocrinologie și Urologie. Hipogonadismul cu debut tardiv este dependent de vârstă și de starea de sănătate a bărbatului. Scăderea nivelului de testosteron poate fi consecința maladiilor cronice, a diabetului, insuficienței de organ sau a obezității. Alte cauze pot fi condiționate de prezența inflamației cronice sistemice. Pacienții în vârstă cu semne ale deficitului de testosteron necesită a fi abordați personalizat pentru a stabili prezența unor forme reversibile/ funcționale de hipogonadism, care pot fi remediate altfel decât terapia de substituție cu testosteron. Administrarea de testosteron este o opțiune de tratament la confirmarea clinică și biochimică a hipogonadismului cu evaluarea potențialelor beneficii și riscuri.

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Descărcări

Publicat

14.04.2026

Număr

Nr. 5(102) (2024)

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Articole

Licență

Această lucrare este licențiată în temeiul Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Cum cităm

[1]

Dumbraveanu, I. et al. 2026. Hipogonadismul bărbatului în vârstă. Repere de diagnostic și tratament. Public Health Economy and Management in Medicine. 5(102) (Apr. 2026), 140–146. DOI:https://doi.org/10.52556/2587-3873.2024.5(102).21.