Dynamics of the molecular marker of intercellular adhesion (icam-1) in patients with neovascular glaucoma after transcleral laser cyclocoagulation

Abstract

The aim of the work was to analyze the dynamics of the peripheral blood inflammatory biomarker in patients with painful neovascular glaucoma and proliferative diabetic retinopathy after transscleral laser cyclocoagulation. 51 patients with painful NVG and PDR were examined. Visual acuity of the better seeing eye was 0.23±0.29. IOP ranged from 29 to 47 mm Hg. Pain syndrome occurred in all patients. LCC was performed according to the standard technique. Patients were administered ketorolac instillations. Results: A significant decrease in IOP and in the symptoms of eye discomfort is dependent on a decrease in the level of the inflammatory biomarker ICAM-1 in the peripheral blood, against the background of long-term (3 months) local anti-inflammatory therapy with ketorolac in patients with NVG on background of PDR after transcleral laser cyclocoagulation.