Rolul uretritelor nongonococice de etiologie bacteriană în infertilitatea masculină

Iurii Arian; Daniela-Patricia Covali; Ion Dumbraveanu; Alan Bogdanov; Gabriela Scripnic; Constantin Tataru; Ion Dumbraveanu

doi:10.52556/2587-3873.2025.3(105).03

Autori

Iurii Arian Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0000-0003-1436-5230
Daniela-Patricia Covali Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0009-0009-7626-7805
Ion Dumbraveanu Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0009-0003-7627-0058
Alan Bogdanov Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0009-0007-4882-3697
Gabriela Scripnic Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0000-0003-3076-9622
Constantin Tataru Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0009-0007-5059-6454
Ion Dumbraveanu Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu“ https://orcid.org/0000-0003-1114-2189

DOI:

https://doi.org/10.52556/2587-3873.2025.3(105).03

Cuvinte cheie:

Uretrita nongonococică, Ureaplasma spp, infertilitate masculină, Mycoplasma spp

Rezumat

Articolul expune date proprii și sinteza literaturii contemporane privind potențialul impact al infecțiilor tractului genital masculin, în special uretritele nongonococice asupra infertilității masculine. Studiul restrospectiv a inclus în total 200 de pacienți din cupluri infertile, cu o cauză inexplicabilă a infertilității, divizați în două loturi: 100 purtători de infecție cu transmitere sexuală și 100 pacienți fără infecție care au constitutit lotul de control. În ambele loturi au fost analizate datele spermogramei, statutul inflamator și markerii endocrini. La 37 (37%) bărbați a fost identificată o infecție unică cu Ureaplasma urealyticum/parvum, la 24 (24%) bărbați – Gardnerella vaginalis, la 32 (32%) de bărbați - Ureaplasma urealiticum/parvum asociată cu Gardnerella vaginalis, la 9 (9%) – Mycoplasma hominis și la 8 (8%) – Mycoplasma genitalium. Analiza comparativă a loturilor atestă diferențe statistic semnificative (p<0,05) în volumul ejaculatului, pH, numărul total de spermatozoizi, concentrația, mobilitatea totală, progresivă și vitalitatea spermatozoizilor, cu valori mult mai reduse în lotul de studiu față de lotul de control. Infecția cu Ureaplasma spp., unică sau în combinație cu alte infecții nongonococice, are un impact semnificativ asupra volumului ejaculatului, pH-ului, numărului total, concentrației, vitalității, mobilității totale și progresive a spermatozoizilor comparativ cu lotul de control.

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Rolul uretritelor nongonococice de etiologie bacteriană în infertilitatea masculină

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