Debitul sanguin volumetric hepatic la bolnavii cu ulcer duodenal

Valentina Platon; Svetlana Turcan; Stela Odobescu; Iulian Negru

Authors

Valentina Platon Nicolae Testemițanu State University of Medicine and Pharmacy https://orcid.org/0000-0003-2109-8476
Svetlana Turcan Nicolae Testemițanu State University of Medicine and Pharmacy https://orcid.org/0000-0002-3348-8466
Stela Odobescu "Diomid Gherman" Institute of Neurology and Neurosurgery https://orcid.org/0000-0001-8184-1220
Iulian Negru Nicolae Testemițanu State University of Medicine and Pharmacy https://orcid.org/0009-0008-1922-2830

Keywords:

anxietate, COVID-19, depression, anxiety

Abstract

The correlation between functional bowel disorders, some organic intestinal disease and psychiatric implication is well known. However, the psycho-emotional state of patients with Clostridioides difficile infection (CDI), particularly in the cases after Covid-19 is not studied enough. The aim of the study was to evaluate depression and anxiety in patients with CDI during the recovery period after Covid-19. Our study included 28 patients with CDI confirmed by enzymatic analysis of glutamate dehydrogenase and toxins A and B in the faeces of patients with nosocomial diarrhea. Depression was assessed on the Hamilton scale (17 points), and anxiety was diagnosed on the Spielberger scale (40 points), including the analysis of reactive anxiety (RA) and personal anxiety (PA). The results of the study show that only 14.3% did not have depression. Mild depression was determined in 75% cases and was significantly more frequent among women. Moderate depression was determined in 10.7% of patients. The most frequent impairment was observed in relatively young people, with a mean age of 57 ± 10.1 years. RA was diagnosed in 42,7% of cases: increased RA - in 28.5%, and highly expressed RA - in 14.2% cases. All patients from the study group had PA: 57.1% had increased PA, and 42.3% - highly expressed PA. Study results confirm the presence of anxiety and depression in an extremely large number of patients with CDI after COVID-19 infection. Such patients should be monitored for early diagnosis of depression and anxiety.

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