Recurrence of varicose disease: causes and pathophysiology mechanisms of its development
Keywords:
recurring varicose, disease, neovascularization, primary varicose veinsAbstract
Varicose dilatation of the lower limbs is an illness that is frequently encountered. According to various data, between 20 to 30% of the adult population worldwide suffers from varicose dilatation. Despite the introduction of numerous types of endovenous interventions, including thermal and chemical ablation of superficial and perforated veins, the fundamental method of correction for varicose disease is the classic „open” surgical intervention. Nevertheless, a common problem after the surgical intervention for patients with chronic varicose disease is residual and recidivante varicose veins. Although there is an increased frequency of recurrent varicose veins of the lower limbs the etiology and pathogenesis of their development remain understudied. In this way, it is not always possible to characterize explicitly the causes of development of recurring veins as a simple deficiency in the planning of the surgical intervention or improper and incomplete execution of the intervention, however the core mechanism is complex and unstudied. Today the causes of the development of recurring varicose disease of the lower limbs are divided in 4 categories: technical mistakes, tactical mistakes, disease progression and neovascularization.
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