Morphology of the sequelae of increased intracranial pressure
Cuvinte cheie:
ischemia, herniation, secondary brain injuriesRezumat
With the introduction of the concept of primary and secondary brain injuries, it became clear that the outcome of one particular cranial-cerebral injury greatly depends on the secondarily initiated mechanisms, which are actually resulting of raised intracranial pressure (ICP). We can conclude about the existence of the raised ICP during person was alive, at the postmortem examination only by its effects on the brain tissue i.e. the signs of internal herniation as sequelae of it. This paper discusses our findings on the sequelae of raised ICP based on neuropathological examination of 80 forensic cases of closed head injury with a survival until 1,5 months. Our findings indicate that the herniation of the brain is going to occur in the first 10,5 days in 90% of the cases and in nearly half of them this deadly consequence can occur in the first 48 hours, which is of great clinical importance.
Referințe
1. Adams, H.J., J.A.N. Corsellis, L.W. Duchen.- Greenfield's neuropathology. 4th edition. John Wiley&Sons. New York, 1984.
2. Adams J.H., D.I. Graham, L.S. Muray, G. Scott. Diffuse axonal injury due to nonmissile head injury in humans: an analysis of 45 cases. Ann.Neurol., 12, 1982, 557-563. https://doi.org/10.1002/ana.410120610
3. Adams J.H., B. Jannet, L.S. Murray, M.G. Teasdale, T.A. Gennarelli, D.I. Graham. Neuropathological findings in disabled survivors of a head injury. - J Neurotrauma., 28, 2011, 701-709. https://doi.org/10.1089/neu.2010.1733
4. Adams, H., D.E. Mitchell, D.I. Graham., D. Doyle. Diffuse brain damage of immediate impact type. Its relationship to "primary brain stem damage" in head injury.- Brain, 100, 1977, (3):489-502. https://doi.org/10.1136/jnnp.54.6.481
5. Davceva N., V. Janevska, B. Ilievski, G. Petrushevska, Z. Popeska. The occurrence of acute subdural haematoma and diffuse axonal injury as two typical acceleration injuries.- J Forensic Leg Med., 19, 2012, 480-484. https://doi.org/10.1016/j.jflm.2012.04.022
6. https://doi.org/10.1016/j.jflm.2012.04.022
7. Davceva N., Janevska V, Ilievski B, R. Jovanovic. The importance of the detail forensic-neuropathological examination in the determination of the diffuse brain injuries. - Soud Lek., 57, 2012, 2-6. https://pubmed.ncbi.nlm.nih. gov/22724588/
8. Dolinak D., E. Matshes. Medicolegal neuropathology. CRC Press New York 2002. https://doi.org/10.1201/9781420040302
9. Finnie J.W. Forensic pathology of traumatic brain injury - Review. Veterinary Pathology. 2016, Vol 53 (5) 962-978. https://doi.org/10.1177/0300985815612155
10. Graham D.I., J.H. Adams, D. Doyle. Ischemic brain damage in fatal non-missile head injuries.- J Neurol Sci., 39,1978, 213-34. https://doi.org/10.1016/0022-510X(78)90124-7
11. Graham D.I., T.A. Gennarelli, T.K. McIntosh. Diffuse (multifocal) brain damage. In: Graham DI, Lantos PL (eds) - Greenfield's neuropathology 7th edn, vol.1. Arnold, London 2002, 854-875
12. Graham D.I., A.E. Lawrence, J.H. Adams, D. Doyle, D.R. Mclellan. Brain damage in non-missile head injury secondary to high intracranial pressure.- Neuropathol Appl Neurobiol., 13, 1987, 209-217. https://doi.org/10.1111/j.1365-2990.1987.tb00184.x
13. Itabashi H.H., J.M. Andrews, U. Tomiyasu, S. Erlich, L. Sathyavagiswaran. Forensic neuropathology. A practical review of the fundamentals. Elsevier 2007. https://doi.org/10.1016/B978-012058527-4/50003-1
14. Kalimo H., P. Saukko, D. Graham. Neuropathological examination in forensic context. Forensic Sci Int., 146, 2004, 73-81. https://doi.org/10.1016/j.forsciint.2004.06.022
15. Miller J.D., J.W. Ironside. Raised intracranial pressure, oedema and hydrocephalus. In: Graham DI, Lantos PL (eds) - Greenfield neuropathology, 6th edn. Arnold, London, 1997, 157-195.
16. Oehmichen M., R.N. Auer, H.G. Konig. Forensic neuropathology and associated neurology. - Springer-Verlag Berlin Heidelberg 2006.
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